Verdona left her home world, Anodyne, in an unspecified time long before the original series and was brought to Earth by a robot alien who had captured her, and wanted to use her to power his planet. They crash landed in St. Louis where she met and fell deeply in love with Max Tennyson, and the two romantically courted each other. During this time she hid her Anodite heritage and blended in with human society. During their time together, Verdona always had to deal with Max's occupation as a Plumber and eventually after a long, happy and yet somewhat distant relationship, they parted.
They had two known children Carl, and Frank. However, neither Carl or Frank inherited her magical and Anodite powers. When they were grown up and out of the house, she returned to Anodyne; after so many years on Earth, Verdona wanted to get back in touch with her background. She once came back to Earth to see if any of her grandchildren had inherited her Anodite abilities and powers, but saw that none did. Only several years later, she found out that Gwen, her granddaughter had.
Like all Anodites, Verdona is a free-spirited being. Though sometimes acting more mature and grown-up, she mostly acts like a playful child. She also likes to listen and dance to Max's favorite band, Shag Carpeting. There is also another side of Verdona which is somewhat amoral and uncaring. For example when she almost destroyed Ben and Kevin when they first confronted her, were it not for the intervention of Gwen and learning who they really were and when she was willing to destroy her granddaughter's physical human body to release the Anodite inside.
Verdona favors Gwen over Ben, due to the fact that Ben didn't inherit her powers and abilities so she just put him aside, which was shown when she magically conjured tape and gagged him on his mouth so he couldn't speak, that was until after their final fight against each other did she see just how much Ben cares about Gwen, the two reconcile on good terms afterward. She also has a uncanny sense of humor that was passed on to Ben. Also, she was shown to be a strict disciplinarian and shown to be serious when she needs to be, when Sunny misbehaved.